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中国人民解放军总医院
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中国人民解放军总医院老年心血管病研究所
中国科技出版传媒股份有限公司
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中华老年多器官疾病杂志编辑委员会
100853, 北京市复兴路28号
电话:010-66936756
传真:010-66936756
E-mail: zhlndqg@mode301.cn
创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
杨栋,胡雯,杜继宇,朱宏,罗继文,刘文,任杰,李金学.老年食管癌患者术后不同营养支持方式临床结局的比较[J].中华老年多器官疾病杂志,2017,16(12):894~897
老年食管癌患者术后不同营养支持方式临床结局的比较
Clinical outcomes of elderly esophageal cancer patients receiving different postoperative nutritional supports:a comparative study
投稿时间:2017-09-04  修订日期:2017-11-08
DOI:10.11915/j.issn.1671-5403.2017.12.208
中文关键词:  老年人;食管肿瘤;营养支持;临床结局
英文关键词:aged; esophageal neoplasms; nutritional support; clinical outcome
基金项目:
作者单位E-mail
杨栋 四川大学 华西公共卫生学院, 成都 610041;绵阳市中心医院临床营养科,绵阳 621000  
胡雯 四川大学华西医院临床营养科, 成都 610041 wendy_nutrition@163.com 
杜继宇 绵阳市中心医院胸心外科,绵阳 621000  
朱宏 绵阳市中心医院胸心外科,绵阳 621000  
罗继文 绵阳市中心医院胸心外科,绵阳 621000  
刘文 绵阳市中心医院胸心外科,绵阳 621000  
任杰 绵阳市中心医院胸心外科,绵阳 621000  
李金学 绵阳市中心医院胸心外科,绵阳 621000  
摘要点击次数: 48
全文下载次数: 50
中文摘要:
      目的 探讨不同营养支持方式对老年食管癌患者术后临床结局的影响。方法 选择2015年11月至2016年8月绵阳市中心医院胸心外科收治的年龄≥60岁的食道癌患者90例,术前采用随机数字表法分为3组:肠内营养(EN)组,肠外营养(PN)组和EN+PN组,每组30例。术后24 h内进行相应的营养支持。观察3组患者体质量亏损、住院时间、住院费用以及肺部感染发生率等指标。采用SPSS 19.0软件进行数据处理。依据数据类型,组间比较分别采用t检验或χ2检验。结果 与EN组相比,PN组患者的体质量亏损显著增加[(7.3±1.3) vs (6.4±1.6)kg],而EN+PN组患者的体质量亏损显著降低[(4.6±1.0) vs (6.4±1.6)kg],差异均具有统计学意义(P<0.05)。EN+PN组患者的术后住院时间及肺部感染发生率均显著少于EN组和PN组(P<0.05),而EN组和PN组的术后住院时间及肺部感染发生率差异无统计学意义(P>0.05)。3组患者住院费用PN组>EN+PN组>EN组,两两比较差异均有统计学意义(P>0.05)。结论 早期肠内联合肠外营养支持对老年食管癌患者术后的临床结局改善效果较好。
英文摘要:
      Objective To determine the effect of different nutritional supports on the clinical outcomes in elderly patients with esophageal cancer after operation.Methods A total of 90 elderly patients with esophageal cancer undergoing surgical treatment in the Department of Thoracic Surgery of Mianyang Central Hospital from November 2015 to August 2016 were enrolled in this study, and were randomly divided into 3 groups before surgery:enteral nutrition (EN) group, parenteral nutrition (PN) group and enteral nutrition combined with parenteral nutrition (EN+PN) group, with 30 cases in each group. All patients were given the corresponding nutritional supports within 24 h after operation.Clinical outcomes were evaluated with body weight loss, length of hospital stay, hospitalization costs, and incidence of pulmonary infection. SPSS statistics 19.0 was used to analyze the date. Student’s t test or Chi-square test was adopted to make the comparison between groups. Results Compared with the patients of EN group, the body mass loss was higher in those of the PN group [(7.3±1.3) vs (6.4±1.6)kg], but lower in those of the EN+PN group [(4.6±1.0) vs (6.4±1.6)kg, both P<0.05]. The EN+PN group had notably shorter length of hospital stay and lower incidence of pulmonary infection than the EN and PN groups (P<0.05), while there were no significant differences between the latter 2 groups (P>0.05).The hospitalization cost was the highest in the PN group, followed by the EN+PN group and the EN group in turn, with obvious difference between mutual groups (P<0.05). Conclusion Early nutritional support with EN+PN is better than others in terms of improving clinical outcomes of the elderly patients with esophageal cancer after surgery.
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