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中国人民解放军总医院老年心血管病研究所
中国科技出版传媒股份有限公司
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中华老年多器官疾病杂志编辑委员会
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创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
张勇胜,黄可可,贺瑜,刘莹,班碧秀.强化谷氨酰胺及合生元的肠内营养对老年住院患者营养状况与胃肠道耐受性的影响[J].中华老年多器官疾病杂志,2017,16(12):898~901
强化谷氨酰胺及合生元的肠内营养对老年住院患者营养状况与胃肠道耐受性的影响
Effects of enteral nutrition with glutamine and synbiotics on nutritional status and gastrointestinal tolerance in elderly inpatients
投稿时间:2017-09-05  修订日期:2017-11-03
DOI:10.11915/j.issn.1671-5403.2017.12.209
中文关键词:  谷氨酰胺;老年人;营养状况;胃肠道耐受性;合生元;肠内营养
英文关键词:glutamine; aged; nutritional status; gastrointestinal tolerance; synbiotics; enteral nutrition
基金项目:
作者单位E-mail
张勇胜 营养学科, 3396398229@qq.com 
黄可可 营养学科,  
贺瑜 营养学科,  
刘莹 老年消化内科,南宁530022  
班碧秀 营养学科,  
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中文摘要:
      目的 研究强化谷氨酰胺和合生元的肠内营养对老年住院患者营养状态与胃肠道耐受性的影响。方法 选取2013年1月至2016年12月于广西医科大学第一附属医院住院并接受肠内营养支持治疗的老年住院患者182例,采用随机数字表法分为两组:治疗组(n=90)和对照组(n=92)。对照组接受常规肠内营养治疗;治疗组在常规肠内营养治疗基础上每天加用谷氨酰胺与合生元。治疗10 d后对比治疗前后两组患者血清白蛋白(ALB)、前白蛋白(PA)和血红蛋白(Hb)水平,同时比较两组患者的胃肠道耐受性。采用SPSS 17.0软件进行数据处理,依据数据类型,组间比较分别采用t检验或χ2检验。结果 治疗后治疗组患者的ALB[(37.16±4.94) vs(33.10±4.97)g/L]、PA[(218.26±89.57) vs(175.12±88.42)mg/L]和Hb[(104.99±16.47) vs(97.04±16.86)g/L]值均显著高于治疗前,差异有统计学意义(P<0.05)。治疗后治疗组的ALB[(37.16±4.94) vs(34.67±4.51)g/L]、PA[(218.26±89.57) vs(211.83±98.39)mg/L]和Hb[(104.99±16.47) vs(102.20±20.35)g/L]值均显著高于对照组,差异有统计学意义(P<0.05)。治疗组腹泻(6.67% vs 16.30%)、腹胀(7.78% vs 20.65%)以及恶心和呕吐(3.33% vs 10.87%)的发生率均显著低于对照组(P<0.05)。结论 强化谷氨酰胺及合生元的肠内营养能够改善老年住院患者的营养状态,提高肠道耐受性。
英文摘要:
      Objective To determine the effects of enteral nutrition with glutamine and synbiotics on nutritional status and gastro-intestinal tolerance in the elderly hospitalized patients. Methods A total of 182 elderly inpatients undergoing enteral nutrition in our hospital from January 2013 to December 2016 were recruited in this study. They were randomly divided into control group (n=92, conventional enteral nutrition) and treatment group (n=90, conventional enteral nutrition and supplements of glutamine and synbiotics). Serum levels of albumin (ALB), prealbumin (PA) and hemoglobin (Hb) prior and 10 d post the treatment were measured and compared. Their gastrointestinal tolerance was observed. Analysis of data was conducted using SPSS statistics 17.0. Differences between groups were compared with Student’s t test or Chi-square test according to different types of data. Results After the treatment, serum levels of ALB [(37.16±4.94) vs (33.10±4.97)g/L], PA [(218.26±89.57) vs (175.12±88.42)mg/L] and Hb [(104.99±16.47) vs (97.04±16.86)g/L] were obviously increased (P<0.05). And the levels were significantly higher in the treatment group than the control group [ALB:(37.16±4.94) vs (34.67±4.51)g/L, PA:(218.26±89.57) vs (211.83±98.39)mg/L, Hb:(104.99±16.47) vs (102.20±20.35)g/L, P<0.05]. The treatment group also had lower incidence rates of diarrhea (6.67% vs 16.30%), bloating (7.78% vs 20.65%), nausea and vomiting (3.33% vs 10.87%) when compared with the control group (P<0.05). Conclusion Enteral nutrition with supplement of glutamine and synbiotcs can improve nutritional status and gastro-intestinal tolerance in elderly patients.
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