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中国人民解放军总医院
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中国人民解放军总医院老年心血管病研究所
中国科技出版传媒股份有限公司
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中华老年多器官疾病杂志编辑委员会
100853, 北京市复兴路28号
电话:010-66936756
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E-mail: zhlndqg@mode301.cn
创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
杨柳,党永康,姜学超.血管介入术治疗老年下肢动脉硬化闭塞症的疗效及安全性分析[J].中华老年多器官疾病杂志,2018,17(8):596~599
血管介入术治疗老年下肢动脉硬化闭塞症的疗效及安全性分析
Efficacy and safety of vascular intervention for treatment of lower extremity atherosclerotic occlusive disease in the elderly
投稿时间:2018-05-03  修订日期:2018-05-28
DOI:10.11915/j.issn.1671-5403.2018.08.136
中文关键词:  血管介入术;下肢动脉硬化闭塞症;临床疗效
英文关键词:vascular interventional therapy; lower extremity atherosclerotic occlusive disease; clinical efficacy
基金项目:
作者单位E-mail
杨柳 赤峰市医院血管外科,赤峰 024000  
党永康 赤峰市医院血管外科,赤峰 024000 dangyongkang@163.com 
姜学超 赤峰市医院血管外科,赤峰 024000  
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中文摘要:
      目的 探讨血管介入术治疗老年下肢动脉硬化闭塞症(LEAOD)的疗效及安全性。方法 回顾性分析2014年7月至2015年12月在赤峰市医院血管外科行腔内血管成形术(PTA)治疗的120例(146条肢体)老年LEAOD患者的临床及随访资料,记录其临床症状缓解情况及并发症的发生率。采用SPSS 17.0软件进行数据处理。依据数据类型,组间比较分别采用t检验或χ2检验。结果 介入成功率为 97.95%(143/146),无死亡病例。与治疗前相比,患者治疗后的足背动脉内径[(1.16±0.32) vs(1.34±0.33)mm]、血流量[(0.52±0.12) vs(0.66±0.13) ml/(s·mm2)]、踝肱指数(ABI)[(0.36±0.11)vs(0.65±0.08)]、跛行距离[(34.53±8.72)vs(633.78±32.56)m]及皮肤温度[(30.03±0.91)℃ vs(33.56±3.45)℃]显著增高,而血流峰值[(51.31±7.85) vs(41.51±6.82)cm/s]和视觉模拟评分量表[(7.12±1.95) vs(0.65±0.12)分]显著降低,差异均具有统计学意义(P<0.05)。术后24个月肢体保全率为100.0%(143/143),无死亡病例。发生再狭窄或闭塞者48例(50条肢体),发生率为35.0%(50/143),其中8例需再次行PTA。结论 血管介入术治疗老年LEAOD患者疗效显著,安全性高。
英文摘要:
      Objective To investigate the efficacy and safety of vascular intervention for the treatment of lower extremity atherosclerotic occlusive disease(LEAOD) in the elderly. Methods A retrospective analysis was made of the clinical and follow-up data from 120 patients (146 limbs) with LEAOD undergoing percutaneous transluminal angioplasty (PTA) at the Department of Vascular Surgery of Chifeng Municipal Hospital from July 2014 to December 2015, and the remission of clinical symptoms and the incidence of complications were recorded. Depending on data type, SPSS statistics 17.0 was used to perform the statistical analysis and t test or Chi-square test was employed for comparison. Results The success rate of intervention was 97.95%(143/146) , and no case died. A statistically significant rise was observed after the procedure in the internal diameter of the dorsal foot artery [(1.16±0.32)vs(1.34±0.33)mm], the blood flow [(0.52±0.12) vs (0.66±0.13) ml/(s·mm2)], ankle brachial index[(0.36±0.11) vs (0.65±0.08)], lame distance [(34.53±8.72) vs (633.78±32.56)m] and skin temperature [(30.03±0.91)℃ vs (33.56±3.45)℃]. The peak velocity of the blood flow [(51.31±7.85) vs (41.51±6.82) cm/s] and visual analogue scale [(7.12±1.95) vs (0.65±0.12) scores] were all significantly lowered after the procedure. All the differences were statistically significant (P<0.05). The limb preservation rate was 100.0%(143/143) within 24 months after the procedure, and no case died. The incidence of restenosis or occlusion was 35.0%(50/143) in 48 patients, with 8 undergoing a second PTA. Conclusion Vascular interventional therapy is effective and safe for LEAOD in the elderly patients.
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