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中国人民解放军总医院老年心血管病研究所
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中华老年多器官疾病杂志编辑委员会
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创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
邓祺丹,杨逸辉,吴培,高靖雯,廖力.糖尿病患者衰弱评估工具预测效能的系统评价[J].中华老年多器官疾病杂志,2020,19(8):566~570
糖尿病患者衰弱评估工具预测效能的系统评价
Predictive validity of frailty assessment instrument in diabetic patients:a syste-matic review and meta-analysis
投稿时间:2019-09-05  
DOI:10.11915/j.issn.1671-5403.2020.08.133
中文关键词:  衰弱;糖尿病;meta分析;预测效能;评估工具
英文关键词:frailty; diabetes mellitus; meta-analysis; predictive performance; assessment instruments This work was supported by the Innovation Project of Graduate Student Scientific Research of Hunan Province
基金项目:湖南省研究生科研创新项目(CX20190763)
作者单位E-mail
邓祺丹 南华大学护理学院,湖南 衡阳 421001 254251558@qq.compredictive 
杨逸辉 南华大学护理学院,湖南 衡阳 421001 254251558@qq.compredictive 
吴培 南华大学护理学院,湖南 衡阳 421001 254251558@qq.compredictive 
高靖雯 南华大学护理学院,湖南 衡阳 421001 254251558@qq.compredictive 
廖力 南华大学护理学院,湖南 衡阳 421001 254251558@qq.compredictive 
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中文摘要:
      目的 了解糖尿病患者衰弱发生率及衰弱评估工具对糖尿病患者不良健康结局的预测效能。方法 计算机检索PubMed、Embase、Web of Science、PEDro、The Cochrane Library、CINAHL、中国知网、万方、中国生物医学文献数据库和维普数据库中关于糖尿病患者衰弱与不良健康结局关系的队列研究,检索时限为2001年1月至2019年4月,按照纳入和排除标准筛选文献并提取资料,采用STATA15.1软件进行Meta分析,对无法合并的资料进行描述性分析。结果 共纳入12项队列研究,563 221例患者。综合分析糖尿病患者衰弱发生率为0.3%~74.0%,衰弱评估工具评估的衰弱情况与糖尿病患者死亡、住院、失能、跌倒等不良健康结局密切相关。Meta分析显示,与其他衰弱评估工具相比,FRAIL是目前在糖尿病患者中应用最广泛的评估工具,且对死亡结局和住院风险具有良好的预测效能。结论 不同工具评估的衰弱发生率差异较大。对于社区老年糖尿病患者进行衰弱的初步简单筛查时,可首选FRAIL量表。但由于纳入研究数量有限,仍需大样本的前瞻性队列研究验证结论。
英文摘要:
      Objective To investigate the prevalence of frailty in diabetic patients and determine the predictive validity of frailty assessment instrument in poor outcome. Methods The cohort studies about poor outcomes of frailty in diabetic patients were searched during January 2001 and April 2019 in the following electronic bibliographic databases, PubMed, Embase, Web of Science, PEDro, and the Cochrane Library, CINAHL, CNKI, Wanfang, CBM and VIP Data. The data were extracted according to inclusion and exclusion criteria. Meta-analysis was conducted by STATA 15.1 software, and descriptive analysis was conducted for data that cannot be combined. Results A total of 12 cohort studies, containing 563221 participants were included. The reported prevalence of frailty ranged from 0.3% to 74.0%. The frailty condition identified by frailty assessment tools were significantly associated with poor outcomes, such as mortality, hospitalization, disability and fall. The meta-analysis revealed that compared with other tools, FRAIL Scale scores were the most widely used tool in diabetic patients, and showed good predictive value for death and hospitalization risks. Conclusion The prevalence of frailty by different tool assessments varies widely in elderly patients with diabetes mellitus. The FRAIL scale is preferred for primary screening for elderly frail patients with diabetes in the community. However, due to limited studies included, prospective cohort study with large sample is still needed to verify the conclusion.
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