Ying ZHOU, Hua-Wei ZHANG, Feng TIAN, Jin-Song CHEN, Tian-Wen HAN, Ya-Hang TAN, Jia ZHOU, Tao ZHANG, Jing JING, Yun-Dai CHEN. Influence of increased epicardial adipose tissue volume on 1-year in-stent restenosis in patients who received coronary stent implantation[J]. Journal of Geriatric Cardiology, 2016, 13(9): 768-775. DOI: 10.11909/j.issn.1671-5411.2016.09.012
Citation: Ying ZHOU, Hua-Wei ZHANG, Feng TIAN, Jin-Song CHEN, Tian-Wen HAN, Ya-Hang TAN, Jia ZHOU, Tao ZHANG, Jing JING, Yun-Dai CHEN. Influence of increased epicardial adipose tissue volume on 1-year in-stent restenosis in patients who received coronary stent implantation[J]. Journal of Geriatric Cardiology, 2016, 13(9): 768-775. DOI: 10.11909/j.issn.1671-5411.2016.09.012

Influence of increased epicardial adipose tissue volume on 1-year in-stent restenosis in patients who received coronary stent implantation

  • Background Epicardial adipose tissue (EAT) is significantly associated with the formation and composition of coronary atherosclerotic plaque, cardiac events and the clinical prognosis of coronary heart disease. But, whether increased EAT deposition may affect the incidence of in-stent restenosis (ISR) is currently unclear. This study used coronary computed tomography angiography (CCTA) as a mean to investigate whether increased EAT volume was associated with ISR. Methods A total of 364 patients who underwent 64-slice CCTA examination for the evaluation of suspected coronary artery disease, and subsequently underwent percutaneous coronary intervention (PCI) for the first time, and then accepted coronary angiography (CA) follow-up for ISR examination in one year, were retrospectively included in this study. EAT volume was measured by CCTA examination. CA follow-up was obtained between 9 and 15 months. ISR was de?ned as ≥ 50% luminal diameter narrowing of the stent segment or peri-stent segment. EAT volume was compared between patients with and without ISR and additional well-known predictors of ISR were compared. Results EAT volume was signi?cantly increased in patients with ISR compared with those without ISR (154.5 ± 74.6 mL vs. 131.0 ± 52.2 mL, P Conclusions EAT volume was related with ISR and may provide additional information for future ISR.
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