Heval Mohamed Kelli, Faisal M Merchant, Andenet Mengistu, Mary Casey, Michael Hoskins, Mikhael F El-Chami. Intermediate-term mortality and incidence of ICD therapy in octogenarians after cardiac resynchronization therapy[J]. Journal of Geriatric Cardiology, 2014, 11(3): 180-184. DOI: 10.11909/j.issn.1671-5411.2014.03.014
Citation: Heval Mohamed Kelli, Faisal M Merchant, Andenet Mengistu, Mary Casey, Michael Hoskins, Mikhael F El-Chami. Intermediate-term mortality and incidence of ICD therapy in octogenarians after cardiac resynchronization therapy[J]. Journal of Geriatric Cardiology, 2014, 11(3): 180-184. DOI: 10.11909/j.issn.1671-5411.2014.03.014

Intermediate-term mortality and incidence of ICD therapy in octogenarians after cardiac resynchronization therapy

  • Background Clinical outcomes of cardiac resynchronization therapy (CRT) in patients over the age of 80 have not been well described. Methods We retrospectively identified 96 consecutive patients ? 80 years old who underwent an initial implant or an upgrade to CRT, with or without defibrillator (CRT-D vs. CRT-P), at our institution between January 2003 and July 2008. The control cohort consisted of 177 randomly selected patients Results In the octogenarian cohort, mean age at CRT implant was 83.1 ± 2.9 years vs. 60.1 ± 8.8 years among controls (P vs. 37%, P vs. 19%, P vs. 27%, P = 0.02) whereas the rate of inappropriate shocks was similar (3% vs. 6%, P = 0.55). At 36 months, there was no significant difference in the rate of all-cause mortality between octogenarians (11%) and controls (8%,P = 0.381). Conclusion Appropriately selected octogenarians who are candidates for CRT have similar intermediate-term mortality compared to younger patients receiving CRT.
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