Please cite this article as: Alachkar MN, Kirschfink A, Alnaimi A, Schröder J, Vogt F, Marx N, Altiok E, Almalla M. Transcatheter mitral valve repair is feasible and effective in oldest-old patients: results from real-world cohort. J Geriatr Cardiol 2022; 19(10): 761−767. DOI: 10.11909/j.issn.1671-5411.2022.10.004.
Citation: Please cite this article as: Alachkar MN, Kirschfink A, Alnaimi A, Schröder J, Vogt F, Marx N, Altiok E, Almalla M. Transcatheter mitral valve repair is feasible and effective in oldest-old patients: results from real-world cohort. J Geriatr Cardiol 2022; 19(10): 761−767. DOI: 10.11909/j.issn.1671-5411.2022.10.004.

Transcatheter mitral valve repair is feasible and effective in oldest-old patients: results from real-world cohort

  •  OBJECTIVE  To evaluate the safety and efficacy of transcatheter mitral valve repair (TMVR) using MitraClip® devices in oldest-old patients compared to younger patients.
     METHODS  The study retrospectively included 340 consecutive patients who underwent TMVR. Patients were classified according to age into the oldest-old (age ≥ 85 years) patient group or the younger (age < 85 years) patient group. Immediate results of the procedure, intrahospital outcomes and one-year outcomes were compared.
     RESULTS  Oldest-old patients represented 15.9% (n = 54) of all patients. Procedure success was comparable for the oldest-old patient group and the younger patient group (92.6% vs. 95.8%, P = 0.30), and there was no difference in intrahospital mortality (9.2% vs. 4.2%, P = 0.12). At a one-year follow-up (interquartile range: 6–16 months), there was no significant difference in rehospitalization due to decompensated heart failure (25.5% vs. 34.3%, P = 0.24) or all-cause mortality (29.8% vs. 22.2%, P = 0.26) between the oldest-old patient group and the younger patient group. In patients with available echocardiographic follow-up, severity of residual mitral regurgitation was also comparable between the oldest-old patient group and the younger patient group.
     CONCLUSIONS  TMVR seems to be feasible and effective in oldest-old patients and should be considered for oldest-old patients presenting with symptomatic severe mitral regurgitation and high surgical risk.
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