ISSN 1671-5411 CN 11-5329/R
Rong-Zeng DU, Jun QIAN, Jun WU, Yi LIANG, Guang-Hua CHEN, Tao SUN, Ye ZHOU, Yang ZHAO, Jin-Chuan YAN. Cardiac resynchronization therapy for heart failure induced by left bundle branch block after transcatheter closure of ventricular septal defect. J Geriatr Cardiol 2014; 11(4): 357-362. doi: 10.11909/j.issn.1671-5411.2014.04.012
Citation: Rong-Zeng DU, Jun QIAN, Jun WU, Yi LIANG, Guang-Hua CHEN, Tao SUN, Ye ZHOU, Yang ZHAO, Jin-Chuan YAN. Cardiac resynchronization therapy for heart failure induced by left bundle branch block after transcatheter closure of ventricular septal defect. J Geriatr Cardiol 2014; 11(4): 357-362. doi: 10.11909/j.issn.1671-5411.2014.04.012

Cardiac resynchronization therapy for heart failure induced by left bundle branch block after transcatheter closure of ventricular septal defect

doi: 10.11909/j.issn.1671-5411.2014.04.012
Funds:

This study was supported by the Social Development Program of Zhenjiang (SH2011024).

  • Received Date: 2014-08-17
  • Rev Recd Date: 2014-10-27
  • Publish Date: 2014-12-06
  • A 54-year-old female patient with congenital heart disease had a persistent complete left bundle branch block three months after closure by an Amplatzer ventricular septal defect occluder. Nine months later, the patient suffered from chest distress, palpitation, and sweating at daily activities, and her 6-min walk distance decreased significantly (155 m). Her echocardiography showed increased left ventricular end-diastolic diameter with left ventricular ejection fraction of 37%. Her symptoms reduced significantly one week after received cardiac resynchronization therapy. She had no symptoms at daily activities, and her echo showed left ventricular ejection fraction of 46% and 53%. Moreover, left ventricular end-diastolic diameter decreased 6 and 10 months after cardiac resynchronization therapy, and 6-min walk distance remarkably increased. This case demonstrated that persistent complete left bundle branch block for nine months after transcatheter closure with ventricular septal defect Amplatzer occluder could lead to left ventricular enlargement and a significant decrease in left ventricular systolic function. Cardiac resynchronization therapy decreased left ventricular end-diastolic diameter and increased left ventricular ejection fraction, thereby improving the patient’s heart functions.
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