ISSN 1671-5411 CN 11-5329/R
Yan DAI, Ke-Ping CHEN, Wei HUA, Jing-Tao ZHANG, Shu ZHANG. Dual antiplatelet therapy increases pocket hematoma complications in Chinese patients with pacemaker implantation. J Geriatr Cardiol 2015; 12(4): 383-387. doi: 10.11909/j.issn.1671-5411.2015.04.010
Citation: Yan DAI, Ke-Ping CHEN, Wei HUA, Jing-Tao ZHANG, Shu ZHANG. Dual antiplatelet therapy increases pocket hematoma complications in Chinese patients with pacemaker implantation. J Geriatr Cardiol 2015; 12(4): 383-387. doi: 10.11909/j.issn.1671-5411.2015.04.010

Dual antiplatelet therapy increases pocket hematoma complications in Chinese patients with pacemaker implantation

doi: 10.11909/j.issn.1671-5411.2015.04.010
  • Received Date: 2015-01-28
  • Rev Recd Date: 2015-03-06
  • Publish Date: 2015-06-12
  • Objective To assess the prevalence of the bleeding complications in pacemaker implanted patients receiving different antiplatelet regimens, and the influence of each regimen on hospital stays after device implantation. Methods We prospectively enrolled 364 patients receiving the cardiac rhythm device implantations in Fuwai Hospital from July 2012 to December 2013. Bleeding complications including pocket hematoma, hemothorax, cardiac tamponade and blood transfusion requirement were measured as endpoints. Post operation hospital stay was also included in the endpoints. Results Bleeding complications were detected in 15 patients (14 with hematoma, one with hemothorax) out of all 364 patients (4.12%). Dual antiplatelet therapy (DAT) significantly increased hematoma (19.3%) compared with aspirin treatment (ASA) (3.2%, P = 0.001) and no antiplatelet therapy (1.9%, P P = 0.45). The post procedure hospital stay was longer in DAT group (5.45 ± 2.01 days) compared to those in the ASA group (3.65 ± 1.37 days, P P P = 0.007). Conclusions Among the Chinese patients undergoing device implantation in this study, the use of dual antiplatelet agents significantly increased the risk of pocket hematoma complications and led to a longer hospital stay. Use of aspirin alone did not increase the risk.
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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