ISSN 1671-5411 CN 11-5329/R
Bo-Yu LI, Xiao-Ming LI, Yan ZHANG, Zhan-Yun WEI, Jing LI, Qi HUA. Effect of coronary artery revascularization on in-hospital outcomes and long-term prognoses in acute myocardial infarction patients with prior is-chemic stroke. J Geriatr Cardiol 2016; 13(2): 145-151. doi: 10.11909/j.issn.1671-5411.2015.06.017
Citation: Bo-Yu LI, Xiao-Ming LI, Yan ZHANG, Zhan-Yun WEI, Jing LI, Qi HUA. Effect of coronary artery revascularization on in-hospital outcomes and long-term prognoses in acute myocardial infarction patients with prior is-chemic stroke. J Geriatr Cardiol 2016; 13(2): 145-151. doi: 10.11909/j.issn.1671-5411.2015.06.017

Effect of coronary artery revascularization on in-hospital outcomes and long-term prognoses in acute myocardial infarction patients with prior is-chemic stroke

doi: 10.11909/j.issn.1671-5411.2015.06.017
Funds:

This study was supported by the National Natural Sci-ence Foundation of China (81470491). We thank all the staff of the Department of Cardiology in Xuanwu Hospital affilitated to the Capital Medical University for their contribution to this study.

  • Received Date: 2015-07-06
  • Rev Recd Date: 2015-11-16
  • Publish Date: 2015-11-16
  • Objective To investigate whether coronary artery revascularization therapies (CART), including percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), can improve the in-hospital and long-term outcomes for acute myocardial infarction (AMI) patients with prior ischemic stroke (IS). Methods A total of 387 AMI patients with prior IS were enrolled consecutively from January 15, 2005 to December 24, 2011 in this cohort study. All patients were categorized into the CART group (n = 204) or the conservative medications (CM) group (n = 183). In-hospital cardiocerebral events and long-term mortality of the two groups after an average follow-up of 36 months were recorded by Kaplan-Meier survival curves and compared by Logistic regression and the Cox regression model. Results The CART patients were younger (66.5 ± 9.7 years vs. 71.7 ± 9.7 years, P P = 0.016) and more multiple-vascular coronary lesions (50% vs. 69.4%, P = 0.031). The hospitalization incidence of cardiocerebral events in the CART group was 9.3% while 26.2% in the CM group (P n = 137) and 24 cases (12.2%) died in CART group (n = 197). Cox regression indicated that CART decreased the long-term mortality by 72% [adjusted hazard ratio (HR) = 0.28, 95% CI: 0.06–0.46], while categorical analysis indicated no significant difference between PCI and CABG. Conclusions CART has a significant effect on improving the in-hospital and long-term prognoses for AMI patients with prior IS.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2069) PDF downloads(1737) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return