ISSN 1671-5411 CN 11-5329/R
Tao TAO, Hao WANG, Shu-Xia WANG, Yu-Tao GUO, Ping ZHU, Yu-Tang WANG. Long-term outcomes of high-risk elderly male patients with multivessel coronary disease: optimal medical therapy versus revascularization. J Geriatr Cardiol 2016; 13(2): 152-157. doi: 10.11909/j.issn.1671-5411.2015.06.020
Citation: Tao TAO, Hao WANG, Shu-Xia WANG, Yu-Tao GUO, Ping ZHU, Yu-Tang WANG. Long-term outcomes of high-risk elderly male patients with multivessel coronary disease: optimal medical therapy versus revascularization. J Geriatr Cardiol 2016; 13(2): 152-157. doi: 10.11909/j.issn.1671-5411.2015.06.020

Long-term outcomes of high-risk elderly male patients with multivessel coronary disease: optimal medical therapy versus revascularization

doi: 10.11909/j.issn.1671-5411.2015.06.020
Funds:

This study was supported by the grant from the Na-tional Natural Science Foundation of China (No. 81100160, 81470504). The authors declare no conflicts of interest.

  • Received Date: 2015-07-22
  • Rev Recd Date: 2015-11-03
  • Publish Date: 2015-12-07
  • Background Many studies have indicated that medical therapy and percutaneous coronary intervention have similar effects in terms of the long-term prognosis of patients with stable coronary artery disease. This study investigated the effects of optimal medical therapy (OMT) and revascularization-plus-OMT in elderly patients with high-risk angina. Methods In this prospective non-randomized study, 241 consecutive high-risk elderly male patients (65–92 years of age) with angiographically confirmed multivessel disease were enrolled in the registry from January 2004 to April 2005. Of these, 98 patients underwent OMT and 143 underwent revascularization therapy plus OMT. Results After 6.5 years of follow-up, we found that the rate of long-term cardiac mortality was significantly higher in patients who underwent OMT than in those who underwent revascularization (6.5-year unadjusted mortality rate, 14.3% for OMT vs. 7.0% for revascularization patients; log-rank P = 0.04). However, the overall risks of major adverse cardiac cerebrovascular events (MACCE) were similar among all patients (6.5-year unadjusted mortality rate, 29.6% for OMT vs. 27.3% for revascularization patients; log-rank P = 0.67). Conclusions OMT was associated with an increase in cardiac death but a similar 6.5-year risk of MACCE compared with revascularization in high-risk elderly male patients with coronary multivessel disease.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2151) PDF downloads(1623) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return