ISSN 1671-5411 CN 11-5329/R
Wen ZHENG, Cheuk–Man YU, Jing LIU, Wu–Xiang XIE, Miao WANG, Yu–Jao ZHANG, Jian SUN, Shao–Ping NIE, Dong ZHAO. Patients with ST-segment elevation of myocardial infarction miss out on early reperfusion: when to undergo delayed revascularization. J Geriatr Cardiol 2017; 14(8): 524-530. doi: 10.11909/j.issn.1671-5411.2017.08.006
Citation: Wen ZHENG, Cheuk–Man YU, Jing LIU, Wu–Xiang XIE, Miao WANG, Yu–Jao ZHANG, Jian SUN, Shao–Ping NIE, Dong ZHAO. Patients with ST-segment elevation of myocardial infarction miss out on early reperfusion: when to undergo delayed revascularization. J Geriatr Cardiol 2017; 14(8): 524-530. doi: 10.11909/j.issn.1671-5411.2017.08.006

Patients with ST-segment elevation of myocardial infarction miss out on early reperfusion: when to undergo delayed revascularization

doi: 10.11909/j.issn.1671-5411.2017.08.006
Funds:

This research was fund by the capital health research and development program (No. Z09050700940901) and the national high technology research and development program (No. 2015AA020102) funded this study.

  • Received Date: 2017-06-09
  • Rev Recd Date: 2017-08-20
  • Publish Date: 2017-08-28
  • Objective There are still a high proportion of patients with ST-segment elevation myocardial infarction (STEMI) missing out early reperfusion even in the primary percutaneous coronary intervention (PCI) era. Most of them are stable latecomers, but the optimal time to undergo delayed PCI for stable ones is controversial. Methods We investigated all STEMI patients who underwent delayed PCI (2–28 days after STEMI) during 2007–2010 in Beijing and excluded patients with hemodynamic instability. The primary outcome was major adverse cardiovascular events (MACEs). Results This study finally enrolled 5,417 STEMI patients and assigned them into three groups according to individual delayed time (early group, 55.9%; median group, 35.4%; late group, 8.7%). During 1-year follow-up, MACEs occurred in 319 patients. The prevalence of MACE were respectively 7.0%, 5.8% and 6.3% (P = 0.272) among three groups. The median group had less recurrent myocardial infarction (P = 0.049) than late group and less repeat revascularization (P = 0.008) than early group in pairwise comparison. We depicted the incidence of MACE by delayed time as a quadratic curve and found the bottom appeared at Day 13–14. Conclusions The time for delayed PCI varied in the real-world practice, but undergoing operations on the second week after STEMI had greater survival benefit and less adverse events for whom without early reperfusion and hemodynamic instability.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (487) PDF downloads(813) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return