ISSN 1671-5411 CN 11-5329/R
Dae-Won Kim, Sung-Ho Her, Ha Wook Park, Kiyuk Chang, Wook Sung Chung, Ki Bae Seung, Myung Ho Jeong, Hyo-Soo Kim, Hyeon Cheol Gwon, In Whan Seong, Kyung Kuk Hwang, Shung Chull Chae, Kwon-Bae Kim, Young Jo Kim, Kwang Soo Cha, Seok Kyu Oh, Jei Keon Chae, Ji-Hoon Jung, on behalf of all KAMIR-NIH Investigators. Incremental age-related one-year MACCE after acute myocardial infarction in the drug-eluting stent era (from KAMIR-NIH registry). J Geriatr Cardiol 2018; 15(9): 574-584. doi: 10.11909/j.issn.1671-5411.2018.09.005
Citation: Dae-Won Kim, Sung-Ho Her, Ha Wook Park, Kiyuk Chang, Wook Sung Chung, Ki Bae Seung, Myung Ho Jeong, Hyo-Soo Kim, Hyeon Cheol Gwon, In Whan Seong, Kyung Kuk Hwang, Shung Chull Chae, Kwon-Bae Kim, Young Jo Kim, Kwang Soo Cha, Seok Kyu Oh, Jei Keon Chae, Ji-Hoon Jung, on behalf of all KAMIR-NIH Investigators. Incremental age-related one-year MACCE after acute myocardial infarction in the drug-eluting stent era (from KAMIR-NIH registry). J Geriatr Cardiol 2018; 15(9): 574-584. doi: 10.11909/j.issn.1671-5411.2018.09.005

Incremental age-related one-year MACCE after acute myocardial infarction in the drug-eluting stent era (from KAMIR-NIH registry)

doi: 10.11909/j.issn.1671-5411.2018.09.005
Funds:

This study was supported by the fund (2016-ER6304- 01) from Research of Korea Centers for Disease Control and Prevention and the Korea Health Technology R & D Project, Ministry of Health & Welfare (HI13C1527), Re?public of Korea.

  • Received Date: 2018-01-11
  • Rev Recd Date: 2018-01-11
  • Publish Date: 2018-09-28
  • Objectives To evaluate the age-related one-year major adverse cardiocerebrovascular events (MACCE) after percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI). We analyzed the association between age and one-year MACCE after AMI. Methods A total of 13,104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institue of Health (KAMIR-NIH) between November 2011 and December 2015 were classified into four groups according to age (Group I, n = 4199; Group II, 60-70 years, n = 2577; Group III; 70-80 years, n = 2774; Group IV, ≥ 80 years, n = 1018). Patients were analyzed for one-year composite of MACCE (cardiac death, myocardial infarction, target vessel revascularization, cerebrovascular events) after AMI. Results The one-year MACCE in AMI were 3.5% (Group I), 6.3% (Group II), 9.6% (Group III) and 17.6% (Group IV). After adjustment for confounding parameters, the analysis results showed that patients with AMI had incremental risk of one-year MACCE [Group II, adjusted hazard ratios (aHR) = 1.224, 95% CI: 0.965-1.525, P = 0.096; Group III, aHR = 1.316, 95% CI: 1.037-1.671, P = 0.024; Group IV, aHR = 1.975, 95% CI: 1.500-62.601, P P = 0.106; Group III, aHR = 1.575, 95% CI: 1.122-2.210, P = 0.009; Group IV, aHR = 2.803, 95% CI: 1.937-4.054, P Conclusions Despite advanced techniques and medications for PCI in AMI, age still exerts a powerful influence in clinical outcomes. Careful approaches, even in the modern era of developed cardiology are needed for aged-population in AMI interven?tion.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (867) PDF downloads(650) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return