ISSN 1671-5411 CN 11-5329/R
Tuoyo O Mene-Afejuku, Ela-Anamaria Moisa, Adedoyin Akinlonu, Carissa Dumancas, Shushan Veranyan, Jose A Perez, Peggy Salazar, Shobhana Chaudhari, Gerald Pekler, Savi Mushiyev, Ferdinand Visco. The relevance of serum albumin among elderly patients with acute decompensated heart failure. J Geriatr Cardiol 2019; 16(7): 522-528. doi: 10.11909/j.issn.1671-5411.2019.07.005
Citation: Tuoyo O Mene-Afejuku, Ela-Anamaria Moisa, Adedoyin Akinlonu, Carissa Dumancas, Shushan Veranyan, Jose A Perez, Peggy Salazar, Shobhana Chaudhari, Gerald Pekler, Savi Mushiyev, Ferdinand Visco. The relevance of serum albumin among elderly patients with acute decompensated heart failure. J Geriatr Cardiol 2019; 16(7): 522-528. doi: 10.11909/j.issn.1671-5411.2019.07.005

The relevance of serum albumin among elderly patients with acute decompensated heart failure

doi: 10.11909/j.issn.1671-5411.2019.07.005
Funds:

None

  • Received Date: 2019-05-06
  • Rev Recd Date: 2019-06-10
  • Publish Date: 2019-07-28
  • Objective To assess the prognostic utility of serum albumin among elderly patients admitted for acute decompensated heart failure (ADHF) in terms of all-cause mortality and also to identify the predictors of hypoalbuminemia. Methods Retrospective cohort study of 119 elderly patients admitted for ADHF. Elderly patients were defined as patients over the age of 65 years. The patients were followed up for approximately 11 years. Patients with advanced renal failure, liver disease not due to HF, cancer and other causes of low life expectancy were excluded. Hypoalbuminemia was defined as serum albumin ≤ 2.9 g/dL. Results The study was made up of 65 females and 54 males with age ranging from 65 to 96 years. Of the 119 elderly patients with ADHF, there were 26 deaths. A significantly higher proportion of patients in the mortality group had an admission serum albumin level of ≤ 2.9 g/dL than those surviving (P = 0.011). After Cox's logistic regression, low albumin (P = 0.016), elevated direct bilirubin (P = 0.03), age greater than 85 (P = 0.008), lack of use of beta blockers (P = 0.0001) and left ventricular ejection fraction less than 35% (P = 0.005) increased the risk of death. Elevated serum creatinine (P = 0.0357) was the only predictor of hypoalbuminemia following multiple linear regression. Conclusions Hypoalbuminemia may be an unrecognized marker of death in elderly patients with ADHF.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (582) PDF downloads(398) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return