ISSN 1671-5411 CN 11-5329/R
Volume 18 Issue 3
Mar.  2021
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Please cite this article as: CAI C, LIU FC, LI JX, HUANG KY, YANG XL, CHEN JC, LIU XQ, CAO J, CHEN SF, SHEN C, YU L, LU FH, WU XP, ZHAO LC, LI Y, HU DS, HUANG JF, ZHOU XY, LU XF, GU DF. Effects of the total physical activity and its changes on incidence, progression, and remission of hypertension. J Geriatr Cardiol 2021; 18(3): 175−184. DOI: 10.11909/j.issn.1671-5411.2021.03.002
Citation: Please cite this article as: CAI C, LIU FC, LI JX, HUANG KY, YANG XL, CHEN JC, LIU XQ, CAO J, CHEN SF, SHEN C, YU L, LU FH, WU XP, ZHAO LC, LI Y, HU DS, HUANG JF, ZHOU XY, LU XF, GU DF. Effects of the total physical activity and its changes on incidence, progression, and remission of hypertension. J Geriatr Cardiol 2021; 18(3): 175−184. DOI: 10.11909/j.issn.1671-5411.2021.03.002

Effects of the total physical activity and its changes on incidence, progression, and remission of hypertension

doi: 10.11909/j.issn.1671-5411.2021.03.002
Funds:  This study was supported by the Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2019-I2M-2-003 and 2017-I2M-1-004), National Key Research & Development Program of China (2018YFE0115300 and 2017YFC0211700, and 2017YFC0908401), and the National Natural Science Foundation of China (91643208). The sources of funding had no role in study design, data collection, analyses, interpretation, and decision to submit the article for publication
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  •  OBJECTIVES Moderate to vigorous physical activity is recommended to prevent hypertension according to the current guidelines. However, the degree to which the total physical activity (TPA) and its changes benefit normotensives and hypertensives is uncertain. We aimed to examine the effects of TPA and its changes on the incidence, progression, and remission of hypertension in the large-scale prospective cohorts.  METHODS A total of 73,077 participants (55,101 normotensives and 17,976 hypertensives) were eligible for TPA analyses. During a mean follow-up of 7.16 years (394,038 person-years), 12,211 hypertension cases were identified. TPA was estimated as metabolic equivalents and categorized into quartiles. Cox proportional hazards regression and multivariable logistic regression were used to estimate associations of TPA and changes in TPA with incident hypertension and progression/remission of hypertension.  RESULTS Compared with the lowest quartile of TPA, normotensives at the third and the highest quartile had a decreased risk of incident hypertension, with hazard ratios (HRs) of 0.86 [95% confidence interval (CI): 0.81−0.91] and 0.81 (95% CI: 0.77−0.86), respectively. Hypertensives at the highest quartile of TPA demonstrated a decreased risk of progression of hypertension [odds ratio (OR) = 0.87, 95% CI: 0.79−0.95], and an increased probability of hypertension remission (OR = 1.17, 95% CI: 1.05−1.29). Moreover, getting active from a sedentary lifestyle during the follow-up period could reduce 25% (HR = 0.75, 95% CI: 0.58−0.96) risk of incident hypertension, whereas those becoming sedentary did not achieve benefit from initially being active.  CONCLUSIONS Our findings indicated that increasing and maintaining TPA levels could benefit normotensives, whereas higher TPA levels were needed to effectively control progression and improve remission of hypertension. Physical activity played undoubtedly an essential role in both primary and secondary prevention of hypertension.
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  • [1]
    GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392: 1923−1994. doi: 10.1016/S0140-6736(18)32225-6
    [2]
    Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365: 217−223. doi: 10.1016/S0140-6736(05)17741-1
    [3]
    Zang J, Ng SW. Age, period and cohort effects on adult physical activity levels from 1991 to 2011 in China. Int J Behav Nutr Phys Act 2016; 13: 40. doi: 10.1186/s12966-016-0364-z
    [4]
    World Health Organization. Global Recommendations on Physical Activity for Health; World Health Organization Press: Switzerland, 2010; 1-58.
    [5]
    Stenehjem JS, Hjerkind KV, Nilsen TIL. Adiposity, physical activity, and risk of hypertension: prospective data from the population-based HUNT Study, Norway. J Hum Hypertens 2018; 32: 278−286. doi: 10.1038/s41371-018-0042-5
    [6]
    Liu X, Zhang D, Liu Y, et al. Dose-Response Association Between Physical Activity and Incident Hypertension: A Systematic Review and Meta-Analysis of Cohort Studies. Hypertension 2017; 69: 813−820. doi: 10.1161/HYPERTENSIONAHA.116.08994
    [7]
    Diaz KM, Booth JN, Seals SR, et al. Physical Activity and Incident Hypertension in African Americans: The Jackson Heart Study. Hypertension 2017; 69: 421−427. doi: 10.1161/HYPERTENSIONAHA.116.08398
    [8]
    Zheng L, Sun Z, Zhang X, et al. Predictors of progression from prehypertension to hypertension among rural Chinese adults: results from Liaoning Province. Eur J Cardiovasc Prev Rehabil 2010; 17: 217−222. doi: 10.1097/HJR.0b013e328334f417
    [9]
    Faselis C, Doumas M, Kokkinos JP, et al. Exercise capacity and progression from prehypertension to hypertension. Hypertension 2012; 60: 333−338. doi: 10.1161/HYPERTENSIONAHA.112.196493
    [10]
    Ng SW, Popkin BM. Time use and physical activity: a shift away from movement across the globe. Obes Rev 2012; 13: 659−680. doi: 10.1111/j.1467-789X.2011.00982.x
    [11]
    Yang X, Li J, Hu D, et al. Predicting the 10-Year Risks of Atherosclerotic Cardiovascular Disease in Chinese Population: The China-PAR Project (Prediction for ASCVD Risk in China). Circulation 2016; 134: 1430−1440. doi: 10.1161/CIRCULATIONAHA.116.022367
    [12]
    Huang K, Yang X, Liang F, et al. Long-Term Exposure to Fine Particulate Matter and Hypertension Incidence in China. Hypertension 2019; 73: 1195−1201. doi: 10.1161/HYPERTENSIONAHA.119.12666
    [13]
    Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J 2018; 39: 3021−3104. doi: 10.1093/eurheartj/ehy339
    [14]
    Han C, Liu F, Yang X, et al. Ideal cardiovascular health and incidence of atherosclerotic cardiovascular disease among Chinese adults: the China-PAR project. Sci China Life Sci 2018; 61: 504−514. doi: 10.1007/s11427-018-9281-6
    [15]
    Garber CE, Blissmer B, Deschenes MR, et al. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc 2011; 43: 1334−1359. doi: 10.1249/MSS.0b013e318213fefb
    [16]
    Ainsworth BE, Haskell WL, Herrmann SD, et al. 2011 Compendium of Physical Activities: a second update of codes and MET values. Med Sci Sports Exerc 2011; 43: 1575−1581. doi: 10.1249/MSS.0b013e31821ece12
    [17]
    Lu J, Lu Y, Wang X, et al. Prevalence, awareness, treatment, and control of hypertension in China: data from 1.7 million adults in a population-based screening study (China PEACE Million Persons Project). Lancet 2017; 390: 2549−2558. doi: 10.1016/S0140-6736(17)32478-9
    [18]
    Eckel RH, Jakicic JM, Ard JD, et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014; 129: S76−99. doi: 10.1161/01.cir.0000437740.48606.d1
    [19]
    Brook RD, Appel LJ, Rubenfire M, et al. Beyond medications and diet: alternative approaches to lowering blood pressure: a scientific statement from the american heart association. Hypertension 2013; 61: 1360−1383. doi: 10.1161/HYP.0b013e318293645f
    [20]
    Nerenberg KA, Zarnke KB, Leung AA, et al. Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. Can J Cardiol 2018; 34: 506−525. doi: 10.1016/j.cjca.2018.02.022
    [21]
    Nakanishi N, Suzuki K. Daily life activity and the risk of developing hypertension in middle-aged Japanese men. Arch Intern Med 2005; 165: 214−220. doi: 10.1001/archinte.165.2.214
    [22]
    Hu G, Barengo NC, Tuomilehto J, et al. Relationship of physical activity and body mass index to the risk of hypertension: a prospective study in Finland. Hypertension 2004; 43: 25−30. doi: 10.1161/01.HYP.0000107400.72456.19
    [23]
    Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013; 31: 1281−1357. doi: 10.1097/01.hjh.0000431740.32696.cc
    [24]
    Floras JS, Sinkey CA, Aylward PE, et al. Postexercise hypotension and sympathoinhibition in borderline hypertensive men. Hypertension 1989; 14: 28−35. doi: 10.1161/01.HYP.14.1.28
    [25]
    Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension 2005; 46: 667−675. doi: 10.1161/01.HYP.0000184225.05629.51
    [26]
    Cleroux J, Kouame N, Nadeau A, et al. Aftereffects of exercise on regional and systemic hemodynamics in hypertension. Hypertension 1992; 19: 183−191. doi: 10.1161/01.HYP.19.2.183
    [27]
    Arakawa K. Antihypertensive mechanism of exercise. J Hypertens 1993; 11: 223−229. doi: 10.1097/00004872-199303000-00001
    [28]
    Pelliccia A, Sharma S, Gati S, et al. 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease. Eur Heart J 2020; 00: 1−80.
    [29]
    Petersen CB, Gronbaek M, Helge JW, et al. Changes in physical activity in leisure time and the risk of myocardial infarction, ischemic heart disease, and all-cause mortality. Eur J Epidemiol 2012; 27: 91−99. doi: 10.1007/s10654-012-9656-z
    [30]
    Florido R, Kwak L, Lazo M, et al. Six-Year Changes in Physical Activity and the Risk of Incident Heart Failure: ARIC Study. Circulation 2018; 137: 2142−2151. doi: 10.1161/CIRCULATIONAHA.117.030226
    [31]
    Leskinen T, Stenholm S, Heinonen OJ, et al. Change in physical activity and accumulation of cardiometabolic risk factors. Prev Med 2018; 112: 31−37. doi: 10.1016/j.ypmed.2018.03.020
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