ISSN 1671-5411 CN 11-5329/R
Mehmet Ozaydin, Ali Kutlucan, Yasin Turker, Banu Koroglu, Akif Arslan, Bayram A. Uysal, Dogan Erdogan, Ercan Varol, Abdullah Dogan1. Association of inflammation with atrial fibrillation in hyperthyroidism. J Geriatr Cardiol 2012; 9(4): 344-348. doi: 10.3724/SP.J.1263.2012.06251
Citation: Mehmet Ozaydin, Ali Kutlucan, Yasin Turker, Banu Koroglu, Akif Arslan, Bayram A. Uysal, Dogan Erdogan, Ercan Varol, Abdullah Dogan1. Association of inflammation with atrial fibrillation in hyperthyroidism. J Geriatr Cardiol 2012; 9(4): 344-348. doi: 10.3724/SP.J.1263.2012.06251

Association of inflammation with atrial fibrillation in hyperthyroidism

doi: 10.3724/SP.J.1263.2012.06251
  • Received Date: 2012-06-25
  • Objectives The aim of this study was to evaluate the relationship between inflammation and development of atrial fibrillation (AF) in patients with hyperthyroidism. Methods A total of 65 patients with newly diagnosed hyperthyroidism, 35 of whom were in sinus rhythm and 30 of whom in AF. Thirty five age- and gender-matched patients in a control group were included in the study. Factors associated with the development of AF were evaluated by multivariate regression analysis. Results Factors associated with AF in multivariate analysis included high sensitivity C reactive protein [(HsCRP); odds ratio (OR): 11.19; 95% confidence interval (95% CI): 1.80-69.53; P = 0.003], free T4 (OR: 8.76; 95% CI: 2.09–36.7; P = 0.003), and left atrial diameter (OR: 1.25; 95% CI: 1.06–1.47; P = 0.008). Conclusions The results of the present study suggest that high sensitivity C reactive protein, an indicator of inflammation, free T4 and left atrial diameter are associated with the development AF in patients with hyperthyroidism.
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