ISSN 1671-5411 CN 11-5329/R
Neelavathi Senkottaiyan, Saad Hafidh, Farrin A. Manian, Martin A. Alpert. Valvular and perivalvular involvement in patients with chronic kidney disease. J Geriatr Cardiol 2005; 2(3): 172-177.
Citation: Neelavathi Senkottaiyan, Saad Hafidh, Farrin A. Manian, Martin A. Alpert. Valvular and perivalvular involvement in patients with chronic kidney disease. J Geriatr Cardiol 2005; 2(3): 172-177.

Valvular and perivalvular involvement in patients with chronic kidney disease

  • Publish Date: 2005-09-28
  • Mitral annular calcification (MAC) and aortic valve calcification (AVC) are the most common valvular and perivalvular abnormalities in patients with chronic kidney disease (CKD). Both MAC and AVC occur at a younger age in CKD patients than in the general population. AVC progresses to aortic stenosis and mild aortic stenosis progresses to severe aortic stenosis at a more rapid rate in patients with CKD than in the general population. The use of calcium-free phosphate binders in such patients may reduce the calcium burden in valvular and perivalvular structures and retard the rate of progression of aortic stenosis. Despite high rates of morbidity and mortality, the prognosis associated with valve surgery in patients with CKD is better than without valve surgery. Infective endocarditis remains an important complication of CKD, particularly in those treated with hemodialysis.
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