ISSN 1671-5411 CN 11-5329/R
Yangchun ZOU, Xingyuan JIA, Xinchun YANG, Liang CUT, Dayi HU, Xiufang HONG. Apolipoprotein E polymorphism in northern Chinese elderly patients with coronary artery disease. J Geriatr Cardiol 2006; 3(2): 95-98.
Citation: Yangchun ZOU, Xingyuan JIA, Xinchun YANG, Liang CUT, Dayi HU, Xiufang HONG. Apolipoprotein E polymorphism in northern Chinese elderly patients with coronary artery disease. J Geriatr Cardiol 2006; 3(2): 95-98.

Apolipoprotein E polymorphism in northern Chinese elderly patients with coronary artery disease

  • Publish Date: 2006-06-28
  • Background and objective Apolipoprotein E is a constituent of lipoproteins with considerable variation due to cysteine-argin-ine exchanges. We investigated the relationship between apo E gene polymorphism and the occurrence of coronary artery disease (CAD) in the older population of northern China. Methods The distribution of the Hhal polymorphisms of the apolipoprotein E gene was determined among 55 patients with CAD (CAD group), which was compared with that of 36 elderly subjects without CAD (control group). Results Genotype distributions at both sites (apo E gene 112-bp and 158-bp sites ) were different between the CAD and control groups. The CAD group had lower apolipoprotein E"el"frequencies than the control group (/><0.05). Conclusion Individu-als with apolipoprotein E"e2"are likely to have a reduced risk of developing coronary artery disease as demonstrated by elderly subjects in Northern China.
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1984) PDF downloads(2199) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return